a recently uploaded flickr set shows a lego creation of fallingwater by frank lloyd wright. by clicking through, i found that this artist has done many other works, including the reitveld chair and villa savoye.
flickr set on fallingwater here.
definitely look at artist’s collection on mocpages (lego community site) here, for other works.
more info via wikipedia:
fallingwater
reitveld (chair)
villa savoye